Certified Neuroscience Registered Nurse (CNRN) Practice Exam

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Prepare for the CNRN Exam. Test your knowledge with our comprehensive multiple-choice questions and detailed explanations. Boost your confidence and improve your chances of a successful exam outcome!

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Which of the following conditions is commonly associated with spina bifida?

The triple screen test
Elevated maternal serum alpha-fetoprotein
Amniocentesis results
Newborn reflex tests

The correct answer is: Elevated maternal serum alpha-fetoprotein

Elevated maternal serum alpha-fetoprotein is a critical marker associated with spina bifida. This condition is characterized by an opening in the spinal column, which can lead to a leakage of cerebrospinal fluid and other components into the mother's bloodstream. As a result, levels of alpha-fetoprotein increase significantly during pregnancy when there are neural tube defects, including spina bifida. Maternal serum alpha-fetoprotein is typically measured during a routine blood test in the second trimester. An elevated level can prompt further investigation, such as ultrasound or amniocentesis, to confirm the presence of spina bifida or other neural tube defects. This elevation serves as a vital screening tool that alerts healthcare providers to potential complications, thus guiding early interventions or counseling for affected families.