Certified Neuroscience Registered Nurse (CNRN) Practice Exam

What type of response causes leukocyte infiltration that can contribute to postoperative ileus?

1. Vascular response

2. Inflammatory response

3. Allergic response

4. Neurological response

The correct answer is: Inflammatory response

The inflammatory response is the correct answer as it plays a significant role in leukocyte infiltration, which can lead to complications like postoperative ileus. After surgical procedures, the body activates its inflammatory pathways in response to tissue injury, infection, or trauma. This activation leads to the release of various mediators such as cytokines, chemokines, and other inflammatory factors. Leukocytes, including neutrophils and macrophages, are recruited to the site of inflammation. Their infiltration helps in the healing process but can also disrupt normal gastrointestinal motility. In the case of postoperative ileus, inflammation can affect nerve function and smooth muscle activity in the intestines, causing a temporary cessation of normal peristalsis, which is crucial for digestive processes. Understanding the role of the inflammatory response in this context is important for recognizing how surgical trauma leads to changes in gastrointestinal function. This knowledge can guide postoperative care and interventions aimed at mitigating ileus and ensuring proper recovery of bowel function.