Certified Neuroscience Registered Nurse (CNRN) Practice Exam

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What is the primary risk factor for developing cholesterol gallstones?

High fiber diet
Low cholesterol intake
Obesity
Aging

The correct answer is: Obesity

The primary risk factor for developing cholesterol gallstones is obesity. Increased body weight is associated with altered cholesterol metabolism, which can lead to higher levels of cholesterol in the bile. This excessive cholesterol can precipitate, forming stones. Obesity is often accompanied by a higher caloric intake and alterations in dietary fat composition, which can further contribute to the risk of cholesterol gallstone formation. While aging, low cholesterol intake, and a high fiber diet may have various impacts on gallstone formation, they do not have the same direct correlation with cholesterol levels in the bile as obesity does. Aging can increase the overall risk but is not as direct a link as the metabolic changes associated with obesity. Similarly, low cholesterol intake and a high fiber diet are generally protective factors against gallstone formation, rather than risk factors.