Certified Neuroscience Registered Nurse (CNRN) Practice Exam

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What is the name of the area in the medulla that is near the 4th ventricle and not protected by the blood-brain barrier?

  1. Vagus Nerve Center

  2. Parabrachial nucleus

  3. Chemoreceptor Trigger Zone (CTZ)

  4. Vestibular nucleus

The correct answer is: Chemoreceptor Trigger Zone (CTZ)

The area in the medulla near the 4th ventricle that is not protected by the blood-brain barrier is known as the Chemoreceptor Trigger Zone (CTZ). This region plays a crucial role in detecting the presence of toxins or chemicals in the blood, which can lead to the stimulation of the vomiting reflex. The lack of a protective barrier allows the CTZ to respond quickly to changes in blood chemistry, making it an essential component in the body’s defense mechanisms against poisoning or adverse substances. This characteristic is significant because it enables the brain to monitor the makeup of the blood and initiate protective responses, like vomiting, when necessary. The other regions mentioned have different functions and their own protective mechanisms, making the CTZ unique in its role and anatomical features.