Certified Neuroscience Registered Nurse (CNRN) Practice Exam

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What is the most common onset time for fat emboli post-operatively?

  1. 12-24 hours post-op

  2. 24-72 hours post-op

  3. 72 hours to 1 week post-op

  4. 1-2 weeks post-op

The correct answer is: 24-72 hours post-op

The most common onset time for fat emboli in the post-operative period typically occurs between 24 to 72 hours post-surgery. This time frame is critical because it aligns with the physiological processes that lead to the release of fat globules into the bloodstream, often as a consequence of trauma or surgery involving the long bones, where fat is stored in the marrow. Fat embolism syndrome is characterized by the presence of fat globules in the circulation, which can result from various surgical procedures. The manifestation of symptoms, such as respiratory distress, neurological deficits, and petechial rash, usually begins within this window (24-72 hours post-operatively), following the release of fat into systemic circulation. Recognizing this timing helps healthcare professionals monitor high-risk patients more effectively, allowing for early identification and management of potential fat embolism complications. Understanding the pathophysiology and timing reinforces the importance of vigilant postoperative monitoring during this crucial period.